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依赖呼吸机的脊髓损伤患者的预期寿命。

Life expectancy of ventilator-dependent persons with spinal cord injuries.

作者信息

DeVivo M J, Ivie C S

机构信息

Department of Rehabilitation Medicine, University of Alabama at Birmingham, USA.

出版信息

Chest. 1995 Jul;108(1):226-32. doi: 10.1378/chest.108.1.226.

Abstract

OBJECTIVE

The purpose of this study is to estimate age-specific life expectancies for ventilator-dependent persons with spinal cord injury (SCI).

DESIGN

Nonconcurrent prospective study.

SETTING

Federally designated model SCI care systems.

PATIENTS

The study included all 435 persons admitted to a model SCI care system between 1973 and 1992 who survived at least 24 h postinjury and who were either ventilator dependent at rehabilitation discharge or who died prior to discharge while still ventilator dependent.

INTERVENTION

None.

OUTCOME MEASURES

Standardized mortality ratio (SMR), life expectancy, and causes of death.

RESULTS

The overall 1-year survival rate was 25.4%, while the 15-year survival rate was 16.8%. Among those who survived the first year, cumulative survival over the next 14 years was 61.4%. The mortality rate for persons injured since 1980 was reduced by 60% compared with persons injured between 1973 and 1979. Among year 1 survivors, the subsequent mortality rate was reduced by 39% for persons injured between 1980 and 1985, and 91% for persons injured since 1986, relative to persons injured between 1973 and 1979. The leading cause of death was respiratory complications, particularly pneumonia.

CONCLUSIONS

With the development of improved methods of prevention and management of respiratory complications in this population, life expectancies should continue to improve. As a result, additional attention should be focused on enhancing the quality of life for these individuals.

摘要

目的

本研究旨在估算脊髓损伤(SCI)依赖呼吸机者的年龄别预期寿命。

设计

非同期前瞻性研究。

地点

联邦指定的脊髓损伤模范护理系统。

患者

本研究纳入了1973年至1992年间入住模范脊髓损伤护理系统的所有435名患者,这些患者在受伤后至少存活24小时,且在康复出院时依赖呼吸机,或在出院前仍依赖呼吸机时死亡。

干预措施

无。

观察指标

标准化死亡率(SMR)、预期寿命和死亡原因。

结果

总体1年生存率为25.4%,15年生存率为16.8%。在存活1年的患者中,接下来14年的累积生存率为61.4%。与1973年至1979年间受伤的患者相比,1980年以后受伤患者的死亡率降低了60%。在第1年存活的患者中,相对于1973年至1979年间受伤的患者,1980年至1985年间受伤患者的后续死亡率降低了39%,1986年以后受伤患者的后续死亡率降低了91%。主要死亡原因是呼吸并发症,尤其是肺炎。

结论

随着该人群呼吸并发症预防和管理方法的改进,预期寿命应会继续提高。因此,应更加关注提高这些个体的生活质量。

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