Edström S, Jacobsson S, Jeppsson P H
Arch Otolaryngol. 1979 Jan;105(1):48-50. doi: 10.1001/archotol.1979.00790130052012.
A case of mucosal melanoma involved the bronchus, maxillary sinus, and small intestine. Treatment with a combination of autologous tumor cells, BCG vaccine, and cytarabine was given, and the immunological system was investigated regularly. After each treatment episode, there was a transient improvement of the cell-mediated immunity to melanoma antigens. The cutaneous delayed hypersensitivity reaction to PPD was converted to a permanently positive one. In the final stage of the disease, the number of T cells was decreased. Difficulty occurred in interpreting the immunological findings according to the clinical condition.
一例黏膜黑色素瘤累及支气管、上颌窦和小肠。给予自体肿瘤细胞、卡介苗和阿糖胞苷联合治疗，并定期研究免疫系统。每次治疗后，针对黑色素瘤抗原的细胞介导免疫有短暂改善。对结核菌素纯蛋白衍生物（PPD）的皮肤迟发型超敏反应转为持续阳性。在疾病的最后阶段，T细胞数量减少。根据临床情况解读免疫结果存在困难。
