Montagna P, Paniccia M, Marchello L, Riva R
Institute of Neurology, University of Bologna, Italy.
Electroencephalogr Clin Neurophysiol. 1995 Jun;97(3):159-63. doi: 10.1016/0924-980x(94)00305-q.
Clinical (paresthesiae and Trousseau's sign), EMG, blood biochemical (lactic acid and total Ca2+) and gas-analytic (pH, PCO2, PO2, HCO3) changes were studied during and after 5 min voluntary hyperventilation (HV) in 15 normal subjects. Paresthesiae and spontaneous motor activity were common manifestations (87% and 67% respectively) in our test. They were significantly related only to changes in pH, PCO2 and PO2, with paresthesiae arising earlier and at milder gas-analytic changes than motor activity. Paresthesiae and motor activity induced by HV cannot be used as reliable indicators of pathology. Their presence simply reflects the degree of the blood gas-analytic changes (pH, PCO2 and PO2) which therefore should be carefully monitored before drawing any conclusion from an HV test.
在15名正常受试者进行5分钟的自主过度通气（HV）期间及之后，研究了临床症状（感觉异常和陶瑟征）、肌电图、血液生化指标（乳酸和总Ca2+）以及气体分析指标（pH、PCO2、PO2、HCO3）的变化。感觉异常和自发运动活动是我们测试中的常见表现（分别为87%和67%）。它们仅与pH、PCO2和PO2的变化显著相关，感觉异常比运动活动出现得更早，且在气体分析变化较轻微时就会出现。HV诱发的感觉异常和运动活动不能用作可靠的病理指标。它们的出现仅仅反映了血气分析变化（pH、PCO2和PO2）的程度，因此在从HV测试得出任何结论之前，都应仔细监测这些指标。
