Krüger D H, Kupper D, Meisel A, Tierlich M, Reuter M, Schroeder C
Institute of Medical Virology, Humboldt University School of Medicine (Charité), Berlin, Germany.
Gene. 1995 May 19;157(1-2):165. doi: 10.1016/0378-1119(95)00699-7.
Simultaneous interaction with two recognition sites was found to be a precondition for DNA cleavage by certain type-II and type-III restriction endonucleases. Nevertheless, the molecular mechanisms of the protein-DNA interaction are different between members of both classes of enzymes.
发现与两个识别位点同时相互作用是某些II型和III型限制性内切核酸酶切割DNA的前提条件。然而,这两类酶成员之间蛋白质与DNA相互作用的分子机制有所不同。