Kelleher J E, Raleigh E A
New England Biolabs, Beverly, MA 01915, USA.
Gene. 1995 May 19;157(1-2):229-30. doi: 10.1016/0378-1119(94)00678-l.
The effect of UV irradiation on restriction mediated by four endogenous restriction systems of E. coli K-12 was investigated using a uniform testing method. Restriction by all four systems was reduced when treated cells were separately challenged with lambda phage carrying modification patterns that elicit restriction by each system. The response of each system was genetically and physiologically distinct.
采用统一的测试方法，研究了紫外线照射对大肠杆菌K-12四种内源性限制系统介导的限制作用的影响。当用携带能引发各系统限制作用的修饰模式的λ噬菌体分别攻击经处理的细胞时，所有四种系统的限制作用均降低。每个系统的反应在遗传和生理上都是不同的。
