Kiene P, Brodersen J P, Fölster-Holst R
Universitäts-Hautklinik, Kiel.
Hautarzt. 1995 May;46(5):349-51. doi: 10.1007/s001050050266.
We report on a 29-year-old female patient with an unusual pigmented lesion of the face. Clinically the lesion looked like a pigment patch of the naevus spilus type, while histological examination revealed the presence of dermal melanocytosis and multiple common blue naevi with a discrete lentiginous component in addition. The melanocytic nature of the infiltrate was ascertained by immunohistochemistry analysis using S 100 protein and HMB 45 antibodies. We interpret this lesion as agminated blue naevi in association with lentigo simplex, an unusual variant of speckled lentiginous naevus.
我们报告了一名29岁的女性患者,其面部有一处不寻常的色素沉着病变。临床上,该病变看起来像斑点状雀斑样痣型色素斑,而组织学检查显示存在真皮黑素细胞增多症以及多个普通蓝痣,此外还有离散的雀斑样成分。通过使用S 100蛋白和HMB 45抗体的免疫组织化学分析确定了浸润的黑素细胞性质。我们将此病变解释为聚集性蓝痣合并单纯性雀斑,这是斑点状雀斑样痣的一种不寻常变体。