Wong C H, Chen S T, Wang K T
Biochim Biophys Acta. 1979 Jan 25;576(1):247-9. doi: 10.1016/0005-2795(79)90500-2.
Protected opioid pentapeptides were synthesized by the papain-catalyzed condensation of small synthetic fragments. These peptides, free as well as protected, were identical with those prepared by the dicyclohexylcarbodiimide-1-hydroxybenzotriazole method.
通过木瓜蛋白酶催化的小合成片段缩合反应合成了受保护的阿片肽五肽。这些游离的以及受保护的肽与通过二环己基碳二亚胺-1-羟基苯并三唑法制备的肽相同。