Ben-Chaim J, Peppas D S, Sponseller P D, Jeffs R D, Gearhart J P
Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, Maryland 21287-2101, USA.
J Urol. 1995 Aug;154(2 Pt 2):865-7. doi: 10.1097/00005392-199508000-00146.
During the last 18 years we treated 22 patients with cloacal exstrophy of whom 13 were referred for further treatment after initial treatment elsewhere. One patient underwent cystectomy with ileal conduit urinary diversion soon after birth and 9 of the remaining 21 underwent initial closure without osteotomy. Of these 9 patients significant complications developed in 8 (89%) after bladder closure, including dehiscence in 6 (1 underwent 2 unsuccessful closures), a vesicocutaneous fistula and postoperative ventral hernia in 1, and bladder prolapse in 1. In contrast, complications developed in only 2 of the 12 patients (17%) who underwent osteotomy at the time of initial closure, including bladder dehiscence in 1 and significant prolapse in 1. Patients who underwent osteotomy and those who did not were similar in terms of the size of omphalocele, presence of myelomeningocele and time of primary closure. We also found that osteotomy or failed closure has no effect on the eventual continence of cloacal exstrophy patients. While osteotomy is not the only variable involved in successful cloacal exstrophy closure, our results indicate the need for osteotomy in these patients to increase the success rate at the time of initial bladder closure.
在过去18年中,我们治疗了22例泄殖腔外翻患者,其中13例在其他地方接受初始治疗后被转诊来接受进一步治疗。1例患者出生后不久即接受了膀胱切除术及回肠导管尿流改道术,其余21例中的9例在未行截骨术的情况下进行了初始闭合。在这9例患者中,8例(89%)在膀胱闭合后出现了严重并发症,包括6例裂开(1例经历了2次未成功的闭合)、1例膀胱皮肤瘘和术后腹疝、1例膀胱脱垂。相比之下,在初始闭合时接受截骨术的12例患者中只有2例(17%)出现并发症,包括1例膀胱裂开和1例严重脱垂。接受截骨术的患者和未接受截骨术的患者在脐膨出大小、脊髓脊膜膨出的存在情况及初次闭合时间方面相似。我们还发现,截骨术或闭合失败对泄殖腔外翻患者最终的控尿情况没有影响。虽然截骨术不是成功闭合泄殖腔外翻所涉及的唯一变量,但我们的结果表明,这些患者需要进行截骨术以提高初次膀胱闭合时的成功率。