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[一种用于评估哺乳动物眼睛电生理信号的计算机程序]

[A PC program for evaluating electrophysiologic signals of mammalian eyes].

作者信息

Kaelin-Lang A, Niemeyer G

机构信息

Neurophysiologie-Labor, Universitäts-Augenklinik Zürich.

出版信息

Klin Monbl Augenheilkd. 1995 May;206(5):394-6. doi: 10.1055/s-2008-1035473.

DOI:10.1055/s-2008-1035473
PMID:7609397
Abstract

BACKGROUND

Electrophysiological measurements in the mammalian eye in vivo or in vitro, i.e. in the arterially perfused cat eye, require storage and analysis of a large amount of data: light-evoked signals, including the electroretinogram (ERG) and the optic nerve response (ONR) are stimulus-related and have to be measured in a triggered mode, whereas the DC-standing potential and flow rate of perfusion medium should be measured continuously.

METHOD AND RESULT

In order to facilitate the analysis of these various signals, we developed a computer program, that allows an on-line data analysis and a trend indication for pharmacologically induced changes in signal size as well as efficient storage. The flexible system is based on a "labview" program, the application and efficiency of which are discussed.

摘要

背景

在哺乳动物眼内进行体内或体外电生理测量,即在动脉灌注的猫眼中进行测量,需要存储和分析大量数据:光诱发信号,包括视网膜电图(ERG)和视神经反应(ONR)与刺激相关,必须以触发模式进行测量,而直流静止电位和灌注介质的流速则应连续测量。

方法与结果

为便于对这些不同信号进行分析,我们开发了一个计算机程序,该程序允许对药理学诱导的信号大小变化进行在线数据分析和趋势指示以及高效存储。这个灵活的系统基于一个“LabVIEW”程序,文中讨论了其应用和效率。

相似文献

1
[A PC program for evaluating electrophysiologic signals of mammalian eyes].[一种用于评估哺乳动物眼睛电生理信号的计算机程序]
Klin Monbl Augenheilkd. 1995 May;206(5):394-6. doi: 10.1055/s-2008-1035473.
2
Changes in glucose level affect rod function more than cone function in the isolated, perfused cat eye.在离体灌注的猫眼中,血糖水平的变化对视杆细胞功能的影响比对视锥细胞功能的影响更大。
Invest Ophthalmol Vis Sci. 1992 Sep;33(10):2798-808.
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[Digital data collection and analysis in clinical electrophysiology. A PC program for electrophysiology].[临床电生理学中的数字数据收集与分析。一个用于电生理学的计算机程序]
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Invest Ophthalmol Vis Sci. 1989 Dec;30(12):2533-6.
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Development of a PC-based system for recording flash electroretinograms in experimental animals.
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[The effect of glucose on rod function in the isolated, perfused cat eye].
Klin Monbl Augenheilkd. 1991 May;198(5):406-7. doi: 10.1055/s-2008-1045993.
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[Use of the scanning laser ophthalmoscope for recording pattern electroretinography and visual evoked cortical potentials].[使用扫描激光检眼镜记录图形视网膜电图和视觉诱发皮层电位]
Klin Monbl Augenheilkd. 1989 Sep;195(3):203-6. doi: 10.1055/s-2008-1046440.
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Effects of insulin under normal and low glucose on retinal electrophysiology in the perfused cat eye.正常血糖和低血糖状态下胰岛素对灌注猫眼视网膜电生理的影响。
Invest Ophthalmol Vis Sci. 1997 Apr;38(5):792-9.
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[Experimental studies of the role of the adrenergic system in the development of bioelectric response of the retina and visual cortex. II. Methodology and characteristics of the ERG and VEP recording].[肾上腺素能系统在视网膜和视觉皮层生物电反应发生中的作用的实验研究。II. 视网膜电图(ERG)和视觉诱发电位(VEP)记录的方法及特点]
Klin Oczna. 1991 Apr-May;93(4-5):108-10.

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