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[根据基于临床分期的方案治疗急性筛窦炎]

[Treatment of acute ethmoiditis according to a protocol based on clinical stage].

作者信息

Middelweerd M J, Bolt R J, van der BURG G J, Kloos R J, Koole F D

机构信息

Afd. Keel-, Neus- en Oorheelkunde, Academisch Ziekenhuis Vrije Universiteit, Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 1995 Jun 24;139(25):1291-5.

PMID:7609805
Abstract

OBJECTIVE

To describe the results of application of a systematic treatment protocol, meant to reduce the risk of serious complications, when treating acute ethmoiditis.

DESIGN

Prospective study.

SETTING

Academic hospital of the 'Vrije Universiteit (VU)', Amsterdam, The Netherlands.

METHOD

From January 1988 to March 1994, 25 children with acute ethmoiditis were admitted to the VU hospital. Eight of them had Chandler stage I, 8 stage II, 3 stage III, 3 stage IV and 3 stage V. The treatment protocol was stepwise, based on the Chandler stages and focused on intensive antibiotic treatment in combination with surgical drainage of the ethmoid complex and (or) the orbit.

RESULTS

All children with ethmoiditis stages I-III were cured without rest symptoms. One patient with ethmoiditis stage IV and a pre-existent lymphatic leukaemia died of pulmonary complications of a massive fungal infection, 8 months after treatment. One patient with ethmoiditis stage V finally had permanent psychomotor retardation.

CONCLUSION

The used treatment protocol offered the possibility to treat patients with acute ethmoiditis stepwise, depending on stage, with satisfying results. Especially the treatment result in patients with ethmoiditis stage V was good.

摘要

目的

描述一种旨在降低治疗急性筛窦炎时严重并发症风险的系统治疗方案的应用结果。

设计

前瞻性研究。

地点

荷兰阿姆斯特丹自由大学(VU)学术医院。

方法

1988年1月至1994年3月,25例急性筛窦炎患儿入住VU医院。其中8例为钱德勒I期,8例II期,3例III期,3例IV期,3例V期。治疗方案是逐步的,基于钱德勒分期,重点是强化抗生素治疗并结合筛窦复合体和(或)眼眶的手术引流。

结果

所有I - III期筛窦炎患儿均治愈,无残留症状。1例IV期筛窦炎患儿,既往有淋巴细胞白血病,治疗8个月后死于大规模真菌感染的肺部并发症。1例V期筛窦炎患儿最终出现永久性精神运动发育迟缓。

结论

所采用的治疗方案为根据分期逐步治疗急性筛窦炎患者提供了可能,结果令人满意。尤其是V期筛窦炎患者的治疗效果良好。

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