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[神经肽对猴子的应激保护作用]

[Stress-protective effect of neuropeptides in monkeys].

作者信息

Dinzburg A L, Chirkov A M, Chirkova S K

出版信息

Patol Fiziol Eksp Ter. 1995 Jan-Mar(1):19-21.

PMID:7609998
Abstract

The effects of endorphin and casomorphin on the behavior and function of steroid-producing glands were tested in 25 male baboons during free behavior and emotional stress caused by a single 2-hour immobilization. The stress-protective effect of peptide preparations was rated by the indices of the individual and social behavior of the monkeys, as well as by the level of corticosteroid and gonad systems. Exogenous opioids on the behavioral and neurohormonal manifestations of the stress-reaction in the baboons were found, which suggests that the use of regulatory peptides is promising as protective agents of emotional stress.

摘要

在25只雄性狒狒自由活动以及由单次2小时固定引起的情绪应激期间,测试了内啡肽和酪蛋白吗啡对类固醇生成腺体的行为和功能的影响。肽制剂的应激保护作用通过猴子的个体和社会行为指标以及皮质类固醇和性腺系统水平来评定。发现外源性阿片类物质对狒狒应激反应的行为和神经激素表现有影响,这表明使用调节肽作为情绪应激的保护剂具有前景。

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