Acorda J A, Yamada H, Ghamsari S M
Department of Veterinary Surgery, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
Vet Q. 1995 Mar;17(1):12-4. doi: 10.1080/01652176.1995.9694522.
Blood samples were collected from 158 Holstein-Friesian cows and analysed for aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transferase and ornithine carabamoyltransferase activities and glucose, total bilirubin, triglyceride, cholesterol-ester and non-esterified fatty acids concentrations. Ultrasonography of the liver was performed, and hepatic ultrasonograms were evaluated subjectively or analysed digitally, and liver samples were examined histopathologically. The diagnostic rates for the different tests were compared. Of the 158 animals, 117 had a normal liver and 41 had fatty infiltration of the liver. For diagnosis of fatty infiltration, digital analysis had the highest sensitivity, specificity, accuracy, and positive and negative predictive values, followed by ultrasonography.
采集了158头荷斯坦-弗里生奶牛的血样，分析了其中天冬氨酸转氨酶、丙氨酸转氨酶、碱性磷酸酶、γ-谷氨酰转移酶和鸟氨酸氨基甲酰转移酶的活性以及葡萄糖、总胆红素、甘油三酯、胆固醇酯和非酯化脂肪酸的浓度。对肝脏进行了超声检查，对肝脏超声图像进行了主观评估或数字分析，并对肝脏样本进行了组织病理学检查。比较了不同检测方法的诊断率。在这158只动物中，117只肝脏正常，41只存在肝脏脂肪浸润。对于肝脏脂肪浸润的诊断，数字分析的敏感性、特异性、准确性以及阳性和阴性预测值最高，其次是超声检查。
