Matsunaga T, Kanzaki J, Hosoda Y
Department of Otolaryngology, School of Medicine, Keio University, Tokyo, Japan.
Acta Otolaryngol Suppl. 1995;519:149-51. doi: 10.3109/00016489509121891.
The transitional region of the eighth cranial nerve, where the central and peripheral nervous tissues are contiguous, was studied by electron microscopy using surgically resected specimens of the human eighth cranial nerve root. The astrocytic glial dome was sharply demarcated by a basement membrane from the peripheral portion of the nerve. Half-desmosomes were found on the edge of the astrocytic glial dome and at the luminal surface of the perivascular glial limiting membrane. Desmosomes and gap junctions were found between the astrocytic processes. These ultrastructural features suggest a weak link between the central and peripheral portions of the nerve which might predispose the transitional region to injury, although the peripheral and central portions have sufficient resistance to external stresses independently.
利用手术切除的人类第八脑神经根部标本，通过电子显微镜对第八脑神经的过渡区域进行了研究，该区域是中枢和外周神经组织相邻的部位。星形胶质细胞胶质穹窿通过基底膜与神经的外周部分清晰分隔。在星形胶质细胞胶质穹窿的边缘和血管周围胶质限制膜的管腔表面发现了半桥粒。在星形胶质细胞突起之间发现了桥粒和缝隙连接。这些超微结构特征表明，神经的中枢和外周部分之间存在薄弱环节，这可能使过渡区域易受损伤，尽管外周和中枢部分各自对外部压力有足够的抵抗力。
