Masutani H, Nakai Y, Kato A
Department of Otolaryngology, Osaka City University Medical School, Japan.
Acta Otolaryngol Suppl. 1995;519:74-7. doi: 10.3109/00016489509121874.
To investigate the role of pathology of the stria vascularis in endolymphatic hydrops, the vascularity and atrophy of the stria were examined by histological observation in guinea pig temporal bones affected by experimental endolymphatic hydrops. Blood cell sludge and vasoconstriction accompanied by strial atrophy were observed in the coiled arteriole and capillary of the stria vascularis of the ear with endolymphatic hydrops after exposure to noise, suggesting the development of inner ear circulatory disturbance. Furthermore, these findings were observed around the upper turn of the cochlea. The effect of glycerol and difenidol hydrochloride on endolymphatic hydrops was also examined. Vasoconstriction and blood cell sludge disappeared following administration of these agents, accompanied by collapse. These findings suggest the possibility that the circulatory disturbance might be the cause of endolymphatic hydrops, followed by strial atrophy.
为研究血管纹病理在膜迷路积水中的作用，通过组织学观察，对实验性膜迷路积水所致豚鼠颞骨中血管纹的血管分布和萎缩情况进行了检查。暴露于噪声后，膜迷路积水耳的血管纹螺旋小动脉和毛细血管中观察到血细胞淤滞和血管收缩，同时伴有血管纹萎缩，提示内耳循环障碍的发生。此外，这些发现出现在耳蜗上转周围。还研究了甘油和盐酸地芬尼多对膜迷路积水的影响。给予这些药物后，血管收缩和血细胞淤滞消失，并伴有塌陷。这些发现提示循环障碍可能是膜迷路积水的原因，继而导致血管纹萎缩。
