Jarvik J G, Philips G R, Schwab C W, Schwartz J S, Grossman R I
Department of Radiology, University of Pennsylvania, Philadelphia, USA.
AJNR Am J Neuroradiol. 1995 Apr;16(4):647-54.
To evaluate penetrating neck trauma for (a) sensitivity of the clinical examination as an indicator of clinically significant vascular injury, and (b) cost-effectiveness of performing screening diagnostic angiography.
The medical records of all patients with penetrating neck trauma presenting at our institution over 4 years were retrospectively reviewed. Injuries were classified into one of three anatomic zones and classified into four mutually exclusive groups based on the extent of vascular injury; (a) no vascular injury; (b) minor vascular abnormality; (c) major vascular abnormality without a change in clinical management; or (d) any injury requiring a change in clinical management. Cost data were also obtained for each patient's hospitalization.
There were 111 patients with penetrating neck trauma. No statistically significant difference between the sensitivities of the clinical examination or angiography for the detection of vascular injury were detected. Of the 48 patients who had vascular injuries, 45 had an abnormal clinical findings (93.7% sensitivity). None of the remaining 3 patients with vascular injury and normal clinical findings would have had their treatment altered by the results of angiography. The calculated cost of using angiography as a screening tool for vascular injury in patients with normal clinical findings was approximately $3.08 million per central nervous system event prevented.
Our study suggests that in patients with zone II penetrating neck injuries the clinical examination is sufficient to detect significant vascular lesions and that screening angiography may not be indicated. Because our sample size was relatively small and the mean follow-up only 13.3 days, further investigation is needed to demonstrate definitively the lack of usefulness of screening angiography.
评估穿透性颈部创伤,以确定(a)临床检查作为具有临床意义的血管损伤指标的敏感性,以及(b)进行筛查诊断性血管造影的成本效益。
回顾性分析了4年间在本机构就诊的所有穿透性颈部创伤患者的病历。损伤被分为三个解剖区域之一,并根据血管损伤程度分为四个相互排斥的组;(a)无血管损伤;(b)轻微血管异常;(c)主要血管异常但临床管理无变化;或(d)任何需要改变临床管理的损伤。还获取了每位患者住院的成本数据。
共有111例穿透性颈部创伤患者。未检测到临床检查或血管造影在检测血管损伤方面的敏感性存在统计学显著差异。在48例有血管损伤的患者中,45例有异常临床发现(敏感性为93.7%)。其余3例有血管损伤但临床发现正常的患者,血管造影结果均不会改变其治疗方案。对于临床发现正常的患者,将血管造影用作血管损伤筛查工具的计算成本约为每预防1例中枢神经系统事件308万美元。
我们的研究表明,对于II区穿透性颈部损伤患者,临床检查足以检测到明显的血管病变,可能无需进行筛查性血管造影。由于我们的样本量相对较小,平均随访仅13.3天,需要进一步研究以明确证明筛查性血管造影无用。