Renoult E, Aymard B, Grégoire M J, Bellou A, Hubert J, Hestin D, Audouin J, Lederlin P, Kessler M
Division of Nephrology, Hôpital de Brabois, University of Nancy, France.
Am J Kidney Dis. 1995 Jul;26(1):84-7. doi: 10.1016/0272-6386(95)90159-0.
A case of an Epstein-Barr virus (EBV)-associated B lymphoproliferative disorder presented as a renal transplant obstruction is reported. The diagnosis was made from histology, immunohistochemistry, and EBV expression studies. Cytogenetic analysis showed the tumor to be of donor origin and revealed chromosomal translocation 46, XY, inv (1)(p35; q41), involving the EBV insertion site 1(1p35) and transforming growth factor beta 2(1q41) loci.
报告了一例表现为肾移植梗阻的爱泼斯坦-巴尔病毒（EBV）相关B淋巴细胞增殖性疾病病例。诊断依据组织学、免疫组化和EBV表达研究做出。细胞遗传学分析显示肿瘤来源于供体，并揭示了染色体易位46, XY, inv(1)(p35; q41)，涉及EBV插入位点1(1p35)和转化生长因子β2(1q41)基因座。
