Kokame G T, de Bustros S
Retina Center at Pali Momi, Aiea, HI 96701, USA.
Am J Ophthalmol. 1995 Jul;120(1):112-4. doi: 10.1016/s0002-9394(14)73768-7.
PURPOSE/METHODS: To evaluate the role of initial visual acuity as a factor for progressive loss of vision or progression to a full-thickness macular hole in eyes with stage I macular holes (tractional foveal detachment without dehiscence). The study population included 35 patients with stage I macular holes with best-corrected visual acuity of 20/25 to 20/80 in one eye, and a full-thickness macular hole in the fellow eye.
RESULTS/CONCLUSIONS: Eyes with stage I macular holes with best corrected visual acuity between 20/50 and 20/80 had a 66% (ten of 15 eyes) rate of progression to full-thickness macular hole, whereas eyes with best-corrected visual acuity of between 20/25 and 20/40 had a 30% (six of 20 eyes) risk of progression to full-thickness macular hole. The risk of progression to macular hole is significantly higher in eyes with stage I macular holes with best-corrected visual acuity of 20/50 or worse (P = .03).
目的/方法：评估初始视力作为I期黄斑裂孔（无裂开的牵引性黄斑脱离）患者视力进行性丧失或进展为全层黄斑裂孔的一个因素的作用。研究人群包括35例单眼最佳矫正视力为20/25至20/80且对侧眼为全层黄斑裂孔的I期黄斑裂孔患者。
结果/结论：最佳矫正视力在20/50至20/80之间的I期黄斑裂孔眼进展为全层黄斑裂孔的发生率为66%（15眼中有10眼），而最佳矫正视力在20/25至20/40之间的眼进展为全层黄斑裂孔的风险为30%（20眼中有6眼）。最佳矫正视力为20/50或更差的I期黄斑裂孔眼进展为黄斑裂孔的风险显著更高（P = 0.03）。
