Yang M W, Kuo T B, Lin S M, Chan K H, Chan S H
Department of Anesthesiology, National Yang-Ming University, Taipei, Taiwan, Republic of China.
Am J Physiol. 1995 Jun;268(6 Pt 2):H2329-35. doi: 10.1152/ajpheart.1995.268.6.H2329.
We communicated the application of continuous, on-line, real-time power spectral analysis of systemic arterial pressure (SAP) signals during cardiopulmonary bypass when the heart was functionally but reversibly disconnected from the blood vessels. Based on observations from 15 cases of successfully completed coronary artery bypass grafting procedures, we found that the very low (0.00-0.08 Hz), low (0.08-0.15 Hz)-, high (0.15-0.25 Hz)-, and very high (0.80-1.60 Hz) frequency components of SAP signals exhibited differential changes before, during, and after cardiopulmonary bypass. In particular, the very low-frequency component, which purportedly represents the contribution of vasomotor activity to SAP, presented only a mild decrease in power during hypothermic cardioplegia. Interestingly, the total peripheral resistance also manifested only a slight reduction during the same period. On the other hand, the low-, high-, and very high frequency components were essentially eliminated. These results unveiled an active role for the blood vessels in the maintenance of SAP during cardiopulmonary bypass, possibly as a result of a maintained vasomotor tone as reflected by the sustained very low frequency component of the SAP signals.
我们阐述了在体外循环期间，当心脏与血管功能上分离但可逆转时，对体动脉压（SAP）信号进行连续、在线、实时功率谱分析的应用。基于15例成功完成冠状动脉旁路移植术的观察结果，我们发现SAP信号的极低频率（0.00 - 0.08Hz）、低频率（0.08 - 0.15Hz）、高频率（0.15 - 0.25Hz）和极高频率（0.80 - 1.60Hz）成分在体外循环前、期间和之后呈现出不同的变化。特别是，据称代表血管运动活动对SAP贡献的极低频率成分，在低温心脏停搏期间仅表现出功率的轻微下降。有趣的是，同期总外周阻力也仅略有降低。另一方面，低、高和极高频率成分基本消失。这些结果揭示了血管在体外循环期间维持SAP中的积极作用，这可能是由于SAP信号持续的极低频率成分所反映的血管运动张力得以维持的结果。
