关于浅表扩散性黑素瘤原发性损害中白色凹陷区域的预后重要性

On the prognostic importance of white depressed areas in the primary lesion of superficial spreading melanoma.

作者信息

McLean D I, Lew R A, Sober A J, Mihm M C, Fitzpatrick T B

出版信息

Cancer. 1979 Jan;43(1):157-61. doi: 10.1002/1097-0142(197901)43:1<157::aid-cncr2820430123>3.0.co;2-s.

DOI:10.1002/1097-0142(197901)43:1<157::aid-cncr2820430123>3.0.co;2-s

Abstract

The lesions of 163 patients with superficial spreading melanoma (SSM) were examined for the presence of white, depressed areas; and lesions with and without these areas of "regression" were compared. There was no statistically significant correlation with the histological level of invasion (Clark-Mihm), sex or age of the patient, location of the melanoma, or presence of local, intransit or regional lymph node metastases. It is apparent from examining the recurrence rate and patient survival, that white depressed areas in an SSM are not of prognostic importance. There was a striking correlation of the presence of white depressed areas with the size of the area covered by the malignant melanoma (p less than or equal to 0.001).

摘要

对163例浅表扩散性黑素瘤（SSM）患者的病灶进行检查，以确定是否存在白色凹陷区域；并对有和没有这些“消退”区域的病灶进行比较。结果发现，其与组织学浸润水平（克拉克-米姆分级）、患者的性别或年龄、黑素瘤的位置，或局部、移行或区域淋巴结转移的存在均无统计学上的显著相关性。从复发率和患者生存率的检查结果来看，SSM中的白色凹陷区域并无预后意义。白色凹陷区域的存在与恶性黑素瘤覆盖区域的大小之间存在显著相关性（p≤0.001）。