Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.

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作者信息

Peterson A R, Peterson H, Heidelberger C

出版信息

Cancer Res. 1979 Jan;39(1):131-8.

PMID:761183

Abstract

摘要

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Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.

Cancer Res. 1979 Jan;39(1):131-8.

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引用本文的文献

Differences in temporal aspects of mutagenesis and cytotoxicity in Chinese hamster cells treated with methylating agents and thymidine.用甲基化剂和胸腺嘧啶核苷处理的中国仓鼠细胞中诱变和细胞毒性时间方面的差异。

Proc Natl Acad Sci U S A. 1982 Mar;79(5):1643-7. doi: 10.1073/pnas.79.5.1643.

Hydrogen bond catalysis of mononucleotide ethylation supports non-random DNA alkylations by N-ethyl, N-nitrosourea.单核苷酸乙基化的氢键催化作用支持N-乙基-N-亚硝基脲对DNA的非随机烷基化作用。

Experientia. 1984 Jul 15;40(7):734-6. doi: 10.1007/BF01949749.

The "promoting" activity of methyl methanesulphonate in rat bladder carcinogenesis.

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Cholesterol epoxide is a direct-acting mutagen.胆固醇环氧化物是一种直接作用的诱变剂。

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HeLa cell variants that differ in sensitivity to monofunctional alkylating agents, with independence of cytotoxic and mutagenic responses.对单功能烷化剂敏感性不同的海拉细胞变体，其细胞毒性和诱变反应相互独立。

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