Williams K P, Wilson S
University of British Columbia, Department of Obstetrics and Gynaecology, Vancouver, Canada.
Am J Perinatol. 1995 May;12(3):189-91. doi: 10.1055/s-2007-994449.
To determine whether there is a difference in middle cerebral blood flow velocity in eclampsia compared to a match control of severe preeclamptic patients in the peripartum phase. Three eclamptic and six preeclamptic women had maternal middle cerebral blood flow velocity assessed antepartum and at 24 and 48 hours postpartum. We compared the effect of an eclamptic convulsion on cerebral blood flow velocity changes using analysis of variance. Cerebral blood flow velocity was significantly higher in eclamptic than in preeclamptic women (p < 0.01) and rose significantly in the post-convulsive phase. Cerebral blood flow velocity was significantly elevated in eclamptic women compared with preeclamptic women in a setting of minimal change in mean arterial pressure.
为确定子痫患者与重度子痫前期患者围产期匹配对照相比，大脑中动脉血流速度是否存在差异。对3例子痫患者和6例重度子痫前期患者在产前、产后24小时和48小时评估母体大脑中动脉血流速度。我们使用方差分析比较子痫抽搐对脑血流速度变化的影响。子痫患者的脑血流速度显著高于重度子痫前期患者（p < 0.01），且在抽搐后阶段显著升高。在平均动脉压变化极小的情况下，子痫患者的脑血流速度与重度子痫前期患者相比显著升高。
