Willoughby J O, Oliver J R, Fletcher T P, Clarke I J
Centre for Neuroscience, Flinders University and Medical Centre, Adelaide, South Australia.
Arch Histol Cytol. 1995 Mar;58(1):31-6. doi: 10.1679/aohc.58.31.
The distribution of somatostatin immunoreactivity was determined throughout the hypothalamus of the sheep and comparisons were made with the known distribution of somatostatin immunoreactivity in the rat. Immunopositive perikarya were present in the sheep periventricular region from as far rostral as the supraoptic recess of the third ventricle to the posterior optic chiasm. In the basal hypothalamus, a thick shell of immunopositive neurons surrounded the ventromedial nucleus (VMH), and there were also neurons in the caudal arcuate nucleus. Somatostatin immunoreactive fibres were concentrated in the dorsal VMH and arcuate nucleus as well as in the median eminence. The distribution in sheep was similar to that in rats, but immunoreactive neurons around sheep VMH were distinctive, a characteristic that might relate to differences in growth hormone physiology in this species.
研究确定了绵羊下丘脑内生长抑素免疫反应性的分布，并与已知的大鼠生长抑素免疫反应性分布进行了比较。在绵羊的室周区域，从第三脑室视上隐窝一直到视交叉后部，均存在免疫阳性核周体。在基底下丘脑，腹内侧核（VMH）周围有一层厚厚的免疫阳性神经元壳，在尾侧弓状核中也有神经元。生长抑素免疫反应性纤维集中在VMH背侧、弓状核以及正中隆起。绵羊体内的分布与大鼠相似，但绵羊VMH周围的免疫反应性神经元具有独特性，这一特征可能与该物种生长激素生理学的差异有关。
