Schowengerdt K O, Towbin J A
Baylor College of Medicine, Houston, Texas, USA.
Curr Opin Cardiol. 1995 May;10(3):312-21. doi: 10.1097/00001573-199505000-00013.
Cardiomyopathies are a major cause of morbidity and mortality worldwide, and currently are the most common group of disorders leading to cardiac transplantation. Recent advances in the field of molecular medicine have provided significant molecular genetic insight into a variety of both primary and secondary cardiomyopathies. The purpose of this review is to briefly describe the known primary and secondary causes of cardiomyopathy; describe the molecular genetic abnormalities associated with them, if known; and describe the current progress being made within this area of molecular cardiology.
心肌病是全球发病和死亡的主要原因，目前是导致心脏移植的最常见疾病组。分子医学领域的最新进展为各种原发性和继发性心肌病提供了重要的分子遗传学见解。本综述的目的是简要描述已知的原发性和继发性心肌病病因；如果已知，描述与之相关的分子遗传异常；并描述分子心脏病学领域目前取得的进展。
