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Induction of an interleukin-1 receptor antagonist-like component produced from mouse spleen cells by bovine kappa-caseinoglycopeptide.

作者信息

Otani H, Monnai M

机构信息

Division of Animal Science, Faculty of Agriculture, Shinshu University, Nagano, Japan.

出版信息

Biosci Biotechnol Biochem. 1995 Jun;59(6):1166-8. doi: 10.1271/bbb.59.1166.

DOI:10.1271/bbb.59.1166
PMID:7613008
Abstract

Bovine kappa-caseinoglycopeptide (residues 106-169, CGP) bound to mouse plastic-adherent cells. A culture supernatant prepared from mouse spleen cells and plastic-adherent cells cultured with CGP significantly inhibited the lipopolysaccharide-induced proliferative response of mouse spleen lymphocytes. The inhibition of proliferation by the culture supernatant was completely overcome by the addition of the anti-interleukin-1 receptor antagonist antibody.

摘要

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