Beasley R, Pearce N, Crane J, Burgess C
Department of Medicine, Wellington School of Medicine, New Zealand.
Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):325-7. doi: 10.1159/000237016.
In response to the evidence that fenoterol was a major cause for the second epidemic of asthma deaths in New Zealand, the Department of Health severely restricted its availability, thereby allowing an 'experiment in prevention' to be undertaken. These regulatory actions, which effectively removed fenoterol from the market in New Zealand, were associated with a sudden and marked reduction in asthma mortality, providing further evidence for a causative role of fenoterol in the epidemic of asthma deaths in New Zealand.
鉴于有证据表明非诺特罗是新西兰哮喘死亡第二次流行的主要原因,卫生部严格限制了其可得性,从而得以进行一项“预防实验”。这些监管行动实际上使非诺特罗在新西兰市场消失,与此同时哮喘死亡率突然显著下降,这进一步证明了非诺特罗在新西兰哮喘死亡流行中起到了致病作用。