Chang F Y, Chou M Y
Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan ROC.
J Formos Med Assoc. 1995 May;94(5):232-7.
A retrospective study on patients with pyogenic liver abscesses was conducted to clarify the different clinical presentations among patients with Klebsiella pneumoniae abscesses and those with non-K. pneumoniae abscesses. From 1981 to 1993, the medical records of 146 adults with culture-confirmed pyogenic liver abscesses who attended Tri-Service General Hospital in Taipei were studied. Abscesses due to K. pneumoniae accounted for 114 (78%) of pyogenic liver abscesses. When compared to patients with non-K. pneumoniae abscesses, patients with K. pneumoniae liver abscesses had significantly higher proportions of monomicrobial infections, unknown sources of infection and solitary abscesses. Patients with K. pneumoniae liver abscesses were found to have diabetes mellitus more often than patients with non-K. pneumoniae liver abscesses (66% vs 19%). Septicemia was found more frequently in patients with K. pneumoniae liver abscesses than in patients with non-K. pneumoniae liver abscesses (50% vs 27%). The clinical presentations among the two groups were, otherwise, not significantly different. Regardless of the microbial etiology, patients with diabetes mellitus had longer periods of fever after treatment and hospitalization than patients without diabetes. The reason for the high relative frequency of liver abscesses in Taiwan and its more frequent occurrence in diabetes mellitus remains unclear.
开展了一项针对化脓性肝脓肿患者的回顾性研究，以阐明肺炎克雷伯菌肝脓肿患者与非肺炎克雷伯菌肝脓肿患者的不同临床表现。1981年至1993年，对台北三军总医院收治的146例经培养确诊为化脓性肝脓肿的成年患者的病历进行了研究。肺炎克雷伯菌引起的脓肿占化脓性肝脓肿的114例（78%）。与非肺炎克雷伯菌肝脓肿患者相比，肺炎克雷伯菌肝脓肿患者的单微生物感染、感染源不明和单发脓肿的比例显著更高。发现肺炎克雷伯菌肝脓肿患者患糖尿病的频率高于非肺炎克雷伯菌肝脓肿患者（66%对19%）。肺炎克雷伯菌肝脓肿患者发生败血症的频率高于非肺炎克雷伯菌肝脓肿患者（50%对27%）。否则，两组的临床表现无显著差异。无论微生物病因如何，糖尿病患者治疗后和住院期间的发热时间均比非糖尿病患者长。台湾肝脓肿相对高发及其在糖尿病患者中更频繁发生的原因尚不清楚。
