针对疾病遗传易感性的人群筛查。
Population screening for genetic susceptibility to disease.
作者信息
Clarke A
机构信息
Department of Medical Genetics, University of Wales College of Medicine, Cardiff.
出版信息
BMJ. 1995 Jul 1;311(6996):35-8. doi: 10.1136/bmj.311.6996.35.
Abstract
Genetic screening for susceptibility to common diseases, such as the common cancers, cardiovascular disease, and diabetes, may soon be technically feasible. Commercial interests should not be allowed to introduce such screening before proper evaluation or without adequate counselling and support. The evaluation of such testing should include psychosocial and medical outcomes and outcomes for those given low risks as well as high risks. These tests may distract attention away from environmental factors contributing to disease, for which social and political measures may be more appropriate than individualised susceptibility screening and lifestyle modification.
摘要
对常见疾病（如常见癌症、心血管疾病和糖尿病）易感性的基因筛查在技术上可能很快就可行了。在进行适当评估之前或没有充分咨询和支持的情况下，不应允许商业利益引入此类筛查。对此类检测的评估应包括心理社会和医学结果，以及低风险和高风险人群的结果。这些检测可能会分散对导致疾病的环境因素的注意力，而对于这些因素，社会和政治措施可能比个性化易感性筛查和生活方式改变更为合适。
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