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Is rotavirus a population of reassortants?

作者信息

Gouvea V, Brantly M

机构信息

Human Genetics Branch, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Trends Microbiol. 1995 Apr;3(4):159-62. doi: 10.1016/s0966-842x(00)88908-8.

DOI:10.1016/s0966-842x(00)88908-8
PMID:7613759
Abstract

Rotaviruses appear to exist as heterogeneous populations of reassortants and related variants. This phenomenon is consistent with the quasispecies concept of RNA viruses, and suggests that gene reassortment is a crucial evolutionary mechanism for this segmented virus. It also explains puzzling epidemiological findings and controversial results of vaccine-efficacy studies.

摘要

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