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Identification of additional homologues of subunits VII and VIII of the ubiquinol-cytochrome c oxidoreductase enables definition of consensus sequences.

作者信息

Boumans H, Berden J A, Grivell L A

机构信息

E.C. Slater Institute, University of Amsterdam, The Netherlands.

出版信息

FEBS Lett. 1995 Jul 10;368(1):105-9. doi: 10.1016/0014-5793(95)00611-c.

DOI:10.1016/0014-5793(95)00611-c
PMID:7615060
Abstract

The Candida utilis QCR7 gene encoding subunit VII of the ubiquinol-cytochrome c oxidoreductase was isolated by functional complementation of the Saccharomyces cerevisiae subunit VII-null mutant. Several other subunit VII homologues as well as homologues for subunit VIII were identified by screening the GenBank database. Some of these homologues for subunit VII could only be identified as such using a consensus sequence that was derived from the multiple sequence alignment. Definition of the consensus should facilitate further analysis of structure/function relationships in this protein.

摘要

相似文献

1
Identification of additional homologues of subunits VII and VIII of the ubiquinol-cytochrome c oxidoreductase enables definition of consensus sequences.
FEBS Lett. 1995 Jul 10;368(1):105-9. doi: 10.1016/0014-5793(95)00611-c.
2
cDNA sequence of subunit VIII of ubiquinol-cytochrome-c oxidoreductase from Schizosaccharomyces pombe.粟酒裂殖酵母泛醇-细胞色素c氧化还原酶亚基VIII的cDNA序列。
Biochim Biophys Acta. 1995 May 10;1229(3):386-8. doi: 10.1016/0005-2728(95)00035-h.
3
The C-terminus of the 14-kDa subunit of ubiquinol-cytochrome-c oxidoreductase of the yeast Saccharomyces cerevisiae is involved in the assembly of a functional enzyme.酿酒酵母泛醇 - 细胞色素c氧化还原酶14-kDa亚基的C末端参与功能性酶的组装。
Eur J Biochem. 1994 Mar 1;220(2):569-76. doi: 10.1111/j.1432-1033.1994.tb18657.x.
4
Topological organization of subunits VII and VIII in the ubiquinol-cytochrome c oxidoreductase of Saccharomyces cerevisiae.
FEBS Lett. 1996 Jul 22;390(2):137-41. doi: 10.1016/0014-5793(96)00642-4.
5
Subunit VII of ubiquinol:cytochrome-c oxidoreductase from Neurospora crassa is functional in yeast and has an N-terminal extension that is not essential for mitochondrial targeting.粗糙脉孢菌泛醇:细胞色素c氧化还原酶的亚基VII在酵母中具有功能,并且有一个N端延伸,该延伸对于线粒体靶向不是必需的。
Biochem J. 1996 Dec 15;320 ( Pt 3)(Pt 3):769-75. doi: 10.1042/bj3200769.
6
Nucleotide sequence of the gene encoding the 11-kDa subunit of the ubiquinol-cytochrome-c oxidoreductase in Saccharomyces cerevisiae.酿酒酵母中泛醇 - 细胞色素c氧化还原酶11-kDa亚基编码基因的核苷酸序列。
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7
The C-terminal half of the 11-kDa subunit VIII is not necessary for the enzymic activity of yeast ubiquinol:cytochrome-c oxidoreductase.11 kDa VIII亚基的C末端一半对于酵母泛醇:细胞色素c氧化还原酶的酶活性不是必需的。
Eur J Biochem. 1989 May 15;181(3):681-7. doi: 10.1111/j.1432-1033.1989.tb14777.x.
8
Inactivation of the gene encoding the 14-kDa subunit VII of yeast ubiquinol. Cytochrome c oxidoreductase and analysis of the resulting mutant.酵母泛醇-细胞色素c氧化还原酶14 kDa亚基VII编码基因的失活及所得突变体的分析。
Eur J Biochem. 1989 May 1;181(2):475-83. doi: 10.1111/j.1432-1033.1989.tb14749.x.
9
The aromatic nature of residue 66 of the 11-kDa subunit of ubiquinol-cytochrome c oxidoreductase of the yeast Saccharomyces cerevisiae is important for the assembly of a functional enzyme.
FEBS Lett. 1994 May 9;344(1):15-9. doi: 10.1016/0014-5793(94)00346-7.
10
Functional complementation analysis of yeast bc1 mutants. A study of the mitochondrial import of heterologous and hybrid proteins.酵母bc1突变体的功能互补分析。异源和杂合蛋白质的线粒体导入研究。
Eur J Biochem. 1999 Sep;264(3):825-32. doi: 10.1046/j.1432-1327.1999.00673.x.

引用本文的文献

1
Subunit VII of ubiquinol:cytochrome-c oxidoreductase from Neurospora crassa is functional in yeast and has an N-terminal extension that is not essential for mitochondrial targeting.粗糙脉孢菌泛醇:细胞色素c氧化还原酶的亚基VII在酵母中具有功能,并且有一个N端延伸,该延伸对于线粒体靶向不是必需的。
Biochem J. 1996 Dec 15;320 ( Pt 3)(Pt 3):769-75. doi: 10.1042/bj3200769.
2
Identification of novel homologues of three low molecular weight subunits of the mitochondrial bc1 complex.线粒体bc1复合体三个低分子量亚基新同源物的鉴定
Mol Biol Rep. 1996;23(2):71-7. doi: 10.1007/BF00424432.