对电离辐射高度敏感的小鼠和中国仓鼠细胞突变体之间的种间互补作用。
Interspecific complementation between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation.
作者信息
Sato K, Chen D J, Eguchi-Kasai K, Itsukaichi H, Odaka T, Strniste G F
机构信息
Division of Radiation Hazards, National Institute of Radiological Sciences, Chiba, Japan.
出版信息
J Radiat Res. 1995 Mar;36(1):38-45. doi: 10.1269/jrr.36.38.
Interspecific and intraspecific hybrids were formed between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation and their radiosensitivities were examined. Chinese hamster cell mutants irs1, irs2 and irs3 and mouse mammary carcinoma cell mutants SX9 and SX10 have been found to belong to five different complementation groups. A radiosensitive mouse lymphoma cell line L5178Y-S has been demonstrated to be different from the X-ray sensitive mouse cell mutants M10 and LX830, both of which are derived from L5178Y cells, in their complementation groups. L5178Y-S is also distinct from SX9 and SX10.
在对电离辐射高度敏感的小鼠和中国仓鼠细胞突变体之间形成了种间和种内杂种，并检测了它们的放射敏感性。已发现中国仓鼠细胞突变体irs1、irs2和irs3以及小鼠乳腺癌细胞突变体SX9和SX10属于五个不同的互补群。已证明放射敏感的小鼠淋巴瘤细胞系L5178Y-S在互补群方面不同于X射线敏感的小鼠细胞突变体M10和LX830，这两个突变体均源自L5178Y细胞。L5178Y-S也与SX9和SX10不同。
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