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[选择性近端迷走神经切断术治疗穿孔性幽门十二指肠溃疡的长期结果]

[Long-term results of selective proximal vagotomy in perforating pyloroduodenal ulcers].

作者信息

Ivanov S V, Podoluzhnyĭ V I

出版信息

Khirurgiia (Mosk). 1995(2):13-5.

PMID:7616696
Abstract

The authors set forth the indications for operation of selective proximal vagotomy (SPV) combined with closure of perforating pyloroduodenal ulcer and note the peculiarities of SPV technique which they apply. They examined 71 persons in periods of up to 7 years after surgery and 41 patients in periods of up to 16 years. The regional acid-proteolytic activity of the stomach was studied. It was established that SPV lowered the aggressiveness of the gastric contents to a safe level. The digestive activity of the gastric juice did not increase in the studied periods. Operation for suturing of a perforating ulcer in the pyloroduodenal zone in combination with SPV causes a high frequency of stable recovery of patients in the late-term periods. The incidence of recurrent peptic ulcer in follow-up periods of up to 16 years was 5.4%.

摘要

作者阐述了选择性近端迷走神经切断术(SPV)联合穿孔性幽门十二指肠溃疡闭合术的手术指征,并指出了他们所采用的SPV技术的特点。他们对术后长达7年的71人以及长达16年的41名患者进行了检查。研究了胃的局部酸蛋白水解活性。结果表明,SPV可将胃内容物的侵袭性降低至安全水平。在研究期间,胃液的消化活性并未增加。幽门十二指肠区穿孔性溃疡缝合术联合SPV可使患者在后期获得较高的稳定康复率。在长达16年的随访期内,复发性消化性溃疡的发生率为5.4%。

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