患有静脉导管的癌症患者的菌血症和真菌血症。

Bacteremia and fungemia in cancer patients with venous catheters.

作者信息

Kukucková E, Studená M, Trupl J, Svec J, Kunová A, Sufliarsky J, Sorkovská D, Minárik T, Sycová Z, Krcméry V

机构信息

Postgraduate Medical School, Bratislava, Slovakia.

出版信息

Neoplasma. 1995;42(1):35-8.

PMID:7617073

Abstract

In 116 cancer patients with bacteremia and fungemia and neutropenia (71%) analysis for the cause was made with regard to the presence of venous catheter, previous therapy or prophylaxis, underlying disease and immunosuppression and etiology. The incidence of bacteremia in patients with catheter was 12x higher (8.25% vs. 0.76%) in comparison to those without catheter and the mortality in respective groups was 26.3% and 15%. Among 206 isolates, 128 (63%) were grampositive aerobes, 58 (27.5%) gramnegative aerobes and 20 (9.5%) fungi. The mortality was the highest in patients with catheter and fungemia (66.6%) and relatively higher in patients with catheter and gramnegative bacteremia.

摘要

对116例患有菌血症、真菌血症且中性粒细胞减少（71%）的癌症患者，就静脉导管的存在情况、先前的治疗或预防措施、基础疾病、免疫抑制及病因进行了病因分析。有导管的患者菌血症发生率比无导管的患者高12倍（8.25%对0.76%），相应组别的死亡率分别为26.3%和15%。在206株分离菌中，128株（63%）为革兰氏阳性需氧菌，58株（27.5%）为革兰氏阴性需氧菌，20株（9.5%）为真菌。导管相关真菌血症患者的死亡率最高（66.6%），导管相关革兰氏阴性菌血症患者的死亡率相对较高。