Hooge J P, Redekop W K
Department of Medicine, University of British Columbia, Vancouver, Canada.
Neurology. 1995 Jul;45(7):1294-6. doi: 10.1212/wnl.45.7.1294.
Trigeminal neuralgia (TN) occurred in 35 patients (1.9%) from a large multiple sclerosis (MS) clinic population (N = 1,882). TN began on average 11.8 years after the first MS symptom but in five patients was the first symptom of MS, preceding the next MS symptom by 1 to 11 years. The onset of MS was later in the patients who had TN, and bilateral TN occurred more frequently than expected (in 14% of TN patients). The age at onset of TN was no younger than in idiopathic TN except when TN was the first MS symptom. Most patients had a good result from medical or surgical therapy.
在一个大型多发性硬化症（MS）门诊人群（N = 1882）中，35名患者（1.9%）出现了三叉神经痛（TN）。TN平均在首次出现MS症状11.8年后开始，但有5名患者TN是MS的首发症状，比下一个MS症状早1至11年。MS的发病在患有TN的患者中较晚，双侧TN的发生频率高于预期（在14%的TN患者中）。除TN是MS的首发症状外，TN的发病年龄不比特发性TN患者年轻。大多数患者通过药物或手术治疗取得了良好效果。
