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[播散性卡氏肺孢子菌感染:1例艾滋病患者的临床病理表现]

[Disseminated Pneumocystis carinii infection: clinico-pathologic findings in an AIDS patient].

作者信息

Valdès E, Borzoni F, Onnis D, Piras S, Vespa A, Varsi C

机构信息

Servizio di Anatomia Patologica, Ospedale SS. Trinità, Cagliari.

出版信息

Pathologica. 1994 Dec;86(6):659-64.

PMID:7617399
Abstract

Pneumocystis carinii pneumonia (PcP) is the most frequent cause of death in AIDS patients. Systemic diffusion of this microorganism is a rare event, mostly reported in patients receiving prophylactic aerosol therapy. The case here described is relative to a 29 years old man with AIDS, dead short by after hospital admission. Radiological and ecoscan examinations revealed structural subversion of liver and spleen, with frequent parenchymal calcification. Post mortem histological examination of lung, liver, spleen, heart, bone marrow, lymph nodes, kidney and hypophysis identified the presence of Pc, confirmed by monoclonal specified antibody immunostaining.

摘要

卡氏肺孢子虫肺炎(PcP)是艾滋病患者最常见的死亡原因。这种微生物的全身扩散是一种罕见事件,大多报道于接受预防性雾化治疗的患者中。此处描述的病例是一名29岁的艾滋病男性患者,入院后不久死亡。放射学和超声检查显示肝脏和脾脏结构破坏,实质内常有钙化。对肺、肝、脾、心、骨髓、淋巴结、肾和垂体进行死后组织学检查,通过单克隆特异性抗体免疫染色确认存在卡氏肺孢子虫。

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