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Autoimmune disorders lead to a sequence of tissue reactions and damage that may produce diffuse, systemic signs and symptoms. Litigants in many breast implants trials have claimed their autoimmune disorders (rheumatoid arthritis, scleroderma, and SLE) were from a causal relationship with mammary implants. Science suggests environmental factors, such as vinyl chloride, and hereditary factors may account for some of the prevalence of these disorders, however the exact cause remains a mystery and brings into question the claims being brought by litigants regarding implants.
自身免疫性疾病会引发一系列组织反应和损伤，可能产生弥漫性的全身症状和体征。许多隆胸植入物试验中的诉讼当事人声称，他们的自身免疫性疾病（类风湿性关节炎、硬皮病和系统性红斑狼疮）与乳房植入物存在因果关系。科学研究表明，诸如氯乙烯等环境因素和遗传因素可能是这些疾病某些发病率的原因，然而确切病因仍是个谜，这也让诉讼当事人关于植入物的说法受到质疑。
