Bianchi S D, Boccardi A, Gandini G
Istituto di Radiologia dell'Università, Torino.
Radiol Med. 1995 May;89(5):586-92.
Osteosarcoma of the jaw differs from that in other sites because it is less aggressive, rarely metastasizes and appears later in life. The literature lacking a systematic treatise on the radiologic features of this disease, the authors decided to collect the case histories of 9 patients, 5 men and 4 women, 24 to 48 years old, suffering from osteosarcoma of the jaw. Both conventional radiography and CT were used to examine all patients. The accurate study of radiologic findings made it possible to establish 3 basic lesion patterns. The first and very rare one, is characterized by the total absence of neoplastic tissue ossification processes; in this case, the radiologic diagnosis is extremely difficult, even with CT support. The second and more common pattern exhibits evident tumor neo-ossification, the most representative cases present several bone lamellae radiating from the lesion, with a sunburst-like appearance. The disease can be diagnosed with conventional radiography alone, especially in the most advanced cases; CT permits the identification of early forms, missed with conventional methods. The third pattern is characterized by amorphous lesion ossification: there are small areas of structureless ossification and a patchy appearance, separated by non-ossified neoplastic tissue. CT shows tumor ossification missed at conventional radiography. Finally, the authors observed an extremely rare case of parosteal sarcoma of the jaw, considered a variety of osteosarcoma by some pathologists. The lesion presented uniform neo-ossification which was highly sclerotic and separated from cortical bone by a thin layer of radiolucent tissue: both findings were clearly visible with CT. In conclusion, the systemic use of CT has led to a marked improvement in the radiologic diagnosis of osteosarcoma of the jaw.
颌骨骨肉瘤与其他部位的骨肉瘤不同,因为它侵袭性较小,很少发生转移,且发病较晚。由于缺乏关于该疾病放射学特征的系统论述,作者决定收集9例颌骨骨肉瘤患者的病历,其中男性5例,女性4例,年龄在24至48岁之间。对所有患者均采用传统X线摄影和CT进行检查。对放射学表现的精确研究使得能够确定3种基本病变模式。第一种非常罕见,其特征是完全没有肿瘤组织的骨化过程;在这种情况下,即使有CT辅助,放射学诊断也极其困难。第二种更常见的模式表现为明显的肿瘤新生骨化,最具代表性的病例呈现出从病变处放射状的多条骨小梁,呈日光放射状外观。仅通过传统X线摄影即可诊断该病,尤其是在最晚期的病例中;CT能够识别出传统方法漏诊的早期病变形式。第三种模式的特征是无定形病变骨化:存在无结构骨化的小区域和斑片状外观,由未骨化的肿瘤组织分隔。CT显示出传统X线摄影漏诊的肿瘤骨化。最后,作者观察到1例极其罕见的颌骨骨膜骨肉瘤病例,一些病理学家认为它是骨肉瘤的一种变体。该病变呈现出均匀的新生骨化,高度硬化,与皮质骨之间由一层薄的透光组织分隔:这两种表现通过CT都清晰可见。总之,CT的系统应用显著提高了颌骨骨肉瘤的放射学诊断水平。