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[计算机断层扫描在精神分裂症患者器质性脑病变诊断中的应用]

[Computerized tomography in the diagnosis of organic brain lesions in patients with schizophrenia].

作者信息

Vavilov S B, Belova O G, Nikiforchuk N M, Savvateeva N Iu, Atiasova E V, Baev A A

出版信息

Vestn Rentgenol Radiol. 1993 May-Jun(3):43-8.

PMID:7618243
Abstract

The authors retrospectively analyse CT data obtained in examinations of 1745 patients divided into three groups. Of these, 832 were male and 913 female patients. Group 1 consisted of 721 patients with schizophrenia, group 2 (reference) consisted of 855 mentally normal subjects directed to computer tomographic examination with suspected organic involvement of the brain, and group 3 (control) consisted of 169 mentally and neurologically normal subjects. On the whole the incidence of various organic brain lesions was 8% in group 1, 41.5% in group 2, and 6.5% in control group, whatever the of the examinees or any other factors. Vascular diseases of the nervous system predominated in group 2 as against group 1, being 3.5 times more incident. No intracranial tumors were detected in controls; in schizophrenics computer tomographic signs of volumic brain lesions were detected in 1.5% of cases, being diagnosed more than 10 times more frequently than in group 2 patients.

摘要

作者回顾性分析了1745例患者的CT检查数据,这些患者被分为三组。其中,男性患者832例,女性患者913例。第一组包括721例精神分裂症患者,第二组(参照组)包括855例因怀疑有脑部器质性病变而接受计算机断层扫描检查的精神正常受试者,第三组(对照组)包括169例精神和神经功能正常的受试者。总体而言,无论受检者情况或任何其他因素如何,第一组各种器质性脑病变的发生率为8%,第二组为41.5%,对照组为6.5%。与第一组相比,第二组以神经系统血管疾病为主,发生率高出3.5倍。对照组未检测到颅内肿瘤;在精神分裂症患者中,1.5%的病例检测到脑容量性病变的计算机断层扫描征象,其诊断频率比第二组患者高出10倍以上。

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