Illényi L, Grexa E, Gecser G, Kött I
1st Department of Surgery, University Medical School, Hungary.
Acta Chir Hung. 1994;34(3-4):333-47.
The authors investigated local recurrence of rectal cancer in patients' groups preoperatively irradiated (40-50 Gy) or treated by surgery alone. In advanced disease both treatment groups were administered postoperative chemotherapy, too. Local recurrence was observed in 30.2% in patients treated by surgery alone, while it dropped to 11.65% in the patients' group subjected to radiation therapy prior to surgery (p < 0.05). Impairment of degree of differentiation resulted in an enhanced number of recurrences in both groups, even if they appeared later in irradiated patients.
作者对术前接受放疗（40 - 50 Gy）或仅接受手术治疗的患者组中直肠癌的局部复发情况进行了研究。在晚期疾病中，两个治疗组也都接受了术后化疗。仅接受手术治疗的患者中局部复发率为30.2%，而术前接受放疗的患者组中该复发率降至11.65%（p < 0.05）。分化程度受损导致两组的复发数量增加，即使放疗患者的复发出现得较晚。
