Pozzessere G, Valle E, Tomaselli M, D'Alessio M, Bianco F, Pierelli F, Morocutti C
Mediterranean Institute of Neuroscience, Pozzilli (Isernia), Italy.
Acta Neurol Belg. 1995;95(2):96-100.
The authors have observed a 33-year-old woman with a 3-year history of a clinical syndrome characterised by atrophy of the musculature of the left foot and leg with impaired motor function, associated with a paracentral cortical oligodendroglioma located in the right parietal region. Clinical, neuroradiological (MRI), electrophysiological (electromyography: EMG; motor evoked potential: MEP; median and tibial somatosensory evoked potential: m-SEP and t-SEP), and neuropsychological studies were performed every year for three years. Neurological examination showed an abnormal gait along with foot drop, pes cavus and pyramidal involvement. MEP and t-SEP recordings were abnormal on the left side, while EMG and neuropsychological tests gave normal results, which were unmodified over time. Our observations suggest that the crural amyotrophy observed in this case may be defined as of "parietal" or "central" origin, a clinical feature which more frequently affects the hand. A review of the literature is presented.
作者观察了一名33岁女性，其临床综合征病史为3年，特征为左足和小腿肌肉萎缩伴运动功能受损，与位于右顶叶区域的中央旁皮质少突胶质细胞瘤有关。连续三年每年进行临床、神经放射学（MRI）、电生理学（肌电图：EMG；运动诱发电位：MEP；正中神经和胫神经体感诱发电位：m-SEP和t-SEP）以及神经心理学研究。神经学检查显示步态异常，伴有足下垂、高弓足和锥体束受累。左侧MEP和t-SEP记录异常，而EMG和神经心理学测试结果正常，且随时间无变化。我们的观察结果表明，该病例中观察到的小腿肌萎缩可能被定义为“顶叶”或“中枢”起源，这是一种更常影响手部的临床特征。本文还对相关文献进行了综述。
