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经食管超声心动图可用于筛查升主动脉动脉粥样硬化。

Transesophageal echocardiography can be used to screen for ascending aortic atherosclerosis.

作者信息

Konstadt S N, Reich D L, Kahn R, Viggiani R F

机构信息

Department of Anesthesiology, Mt. Sinai Medical Center, New York, New York 10029, USA.

出版信息

Anesth Analg. 1995 Aug;81(2):225-8. doi: 10.1097/00000539-199508000-00003.

Abstract

Atherosclerosis of the ascending aorta may be associated with a higher perioperative stroke risk in cardiac surgery. This study investigated the use of biplane transesophageal echocardiography (TEE) scanning of the entire thoracic aorta to predict the presence of plaque in the ascending aorta. Eighty-one patients (57 male, 24 female; aged 32-88 yr, mean age 64 yr) scheduled for elective cardiac surgery participated in an institutional review board-approved protocol. A comprehensive examination of the entire thoracic aorta in both the longitudinal and transverse planes was performed. After pericardiotomy, a sterilely draped 7-MHz probe was used to scan the entire ascending aorta in both long and short axis views. In both echocardiographic examinations, the presence and location of protruding plaques and intimal thickening > 3 mm were recorded. Using epiaortic (EPI) scanning as the "gold standard," the sensitivity, specificity, positive predictive value, and negative predictive value of TEE for detecting ascending aortic atherosclerosis were calculated. Fourteen (17%) of the 81 patients had significant atherosclerotic disease of the ascending aorta as diagnosed by EPI echocardiography. The sensitivity of TEE was 100%, the specificity was 60%, the positive predictive value was 34%, and the negative predictive value was 100%. These data show that, if the complete biplane TEE examination is negative for plaque, it is highly unlikely that there is significant plaque in the ascending aorta. If the TEE examination is positive for plaque, there is a 34% chance that there is significant disease of the ascending aorta, and EPI scanning should be considered. Thus, TEE is a very sensitive but only mildly specific method of determining whether ascending aortic atherosclerosis is present.

摘要

升主动脉粥样硬化可能与心脏手术中较高的围手术期卒中风险相关。本研究调查了使用双平面经食管超声心动图(TEE)扫描整个胸主动脉以预测升主动脉中斑块的存在情况。81例计划进行择期心脏手术的患者(57例男性,24例女性;年龄32 - 88岁,平均年龄64岁)参与了一项经机构审查委员会批准的方案。对整个胸主动脉进行了纵切面和横切面的全面检查。心包切开术后,使用无菌覆盖的7MHz探头在长轴和短轴视图下扫描整个升主动脉。在两次超声心动图检查中,记录突出斑块的存在和位置以及内膜增厚>3mm的情况。以主动脉外膜(EPI)扫描作为“金标准”,计算TEE检测升主动脉粥样硬化的敏感性、特异性、阳性预测值和阴性预测值。81例患者中有14例(17%)经EPI超声心动图诊断为升主动脉存在显著的动脉粥样硬化疾病。TEE的敏感性为100%,特异性为60%,阳性预测值为34%,阴性预测值为100%。这些数据表明,如果完整的双平面TEE检查未发现斑块,则升主动脉中存在显著斑块的可能性极小。如果TEE检查发现斑块呈阳性,则升主动脉存在显著疾病的可能性为34%,应考虑进行EPI扫描。因此,TEE是一种非常敏感但特异性仅为中等程度的确定升主动脉粥样硬化是否存在的方法。

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