Smith J, Spurrier N, Goggin M
Department of Ophthalmology, Flinders Medical Centre, South Australia.
Aust N Z J Ophthalmol. 1995 Feb;23(1):49-54.
To establish the incidence and severity of retinopathy of prematurity (ROP) in an Australian population of premature infants, and define risk factors for this population.
A survey of neonates born weighing less than 1501 g and/or with gestational age below 33 weeks, was undertaken at a neonatal intensive care unit in South Australia.
ROP was diagnosed in 16.0% of the 94 neonates who were screened until retinal vascularisation was complete. Threshold disease occurred in 4.2%. Logistic regression identified three significant risk factors for the development of ROP: days of mechanical ventilation, multiple birth and female sex.
The incidence of ROP was relatively low when compared with figures recently published for two large populations studied in the United States and England. This difference was due to a lower incidence of mild forms of the disease. Days of mechanical ventilation, multiple birth and female sex were independently predictive of the occurrence of ROP. As small numbers of infants with ROP are managed at individual Australian centres each year, a national ROP register is recommended to facilitate the study of the disease in this country.
确定澳大利亚早产婴儿群体中早产儿视网膜病变（ROP）的发病率和严重程度，并明确该群体的风险因素。
在南澳大利亚的一家新生儿重症监护病房，对出生体重小于1501克和/或胎龄低于33周的新生儿进行了一项调查。
在94名接受筛查直至视网膜血管化完成的新生儿中，16.0%被诊断为ROP。阈值疾病发生率为4.2%。逻辑回归确定了ROP发生的三个重要风险因素：机械通气天数、多胎妊娠和女性性别。
与最近在美国和英国研究的两个大群体公布的数据相比，ROP的发病率相对较低。这种差异是由于该疾病轻度形式的发病率较低。机械通气天数、多胎妊娠和女性性别可独立预测ROP的发生。由于澳大利亚各中心每年管理的ROP婴儿数量较少，建议建立全国ROP登记册，以促进该国对该疾病的研究。
