Tisner Nieto J V, Fraile Rodrigo J, Oritz García A, Giraldo Castellano M P, Giralt Raichs M
Hospital Miguel Severt, Zaragoza.
Acta Otorrinolaringol Esp. 1995 May-Jun;46(3):235-8.
Assessment of the incidence, diagnosis and treatment of three patients afflicted of extramedullary plasmacytoma located in the Waldeyer's ring, and one case afflicted of maxillary sinus disease.
The localization of the masses was the palatine amygdala in two cases, and the rhinopharynx and maxillary sinus in the remaining two patients. Major symptoms were dysphagia respiratory failure with closed rhinolalia, and headache. Diagnosis was made by histological study of biopsied tissue. In every case, general illness or other site of localization were ruled out.
In our casuistic, the incidence of primary extramedullary plasmacytoma in Waldeyer's ring is 1.2%. The patient's age were 45, 50, 62, and 73 years respectively, and the male/female ratio was 1. In those cases located in the tonsils, a bilateral tonsillectomy was performed. In the case located at the maxillary sinus, a sinus trepanation was performed according the Caldwell-Luc's technique, followed by local radiotherapy at doses of 40 Gy. In the case located at the rhinopharynx, radiotherapy was the only choice. These three different therapeutical procedures led to the disappearance of the disease, and, after a 12 to 53 month-period, patients remain asymptomatic. A patient died due to other causes not related to the illness.
评估3例位于瓦尔代尔环的髓外浆细胞瘤患者以及1例上颌窦疾病患者的发病率、诊断及治疗情况。
肿物的位置在2例患者中位于腭扁桃体，在另外2例患者中位于鼻咽部和上颌窦。主要症状为吞咽困难、伴有闭塞性鼻音的呼吸衰竭以及头痛。通过对活检组织进行组织学研究做出诊断。在每例病例中，均排除了全身性疾病或其他定位部位。
在我们的病例中，瓦尔代尔环原发性髓外浆细胞瘤的发病率为1.2%。患者年龄分别为45岁、50岁、62岁和73岁，男女比例为1。对于位于扁桃体的病例，实施了双侧扁桃体切除术。对于位于上颌窦的病例，按照考德威尔-卢氏技术进行了鼻窦环钻术，随后给予40 Gy的局部放疗。对于位于鼻咽部的病例，放疗是唯一选择。这三种不同的治疗方法均使疾病消失，并且在12至53个月的时间段后，患者仍无症状。1例患者因与疾病无关的其他原因死亡。
