McDougall A C
Int J Dermatol. 1979 Jan-Feb;18(1):46-9. doi: 10.1111/j.1365-4362.1979.tb01911.x.
A 45-year-old Pakistani woman reported to a clinic in Karachi with a one-year history of hypopigmented lesions on the left side of the face and neck. On first presentation the lesions were rough-surfaced and hypoaesthetic; the clinical findings in this highly endemic area of the world suggested macular tuberculoid leprosy. The patient was treated with dapsone for a period of 5 years, but with no change in the appearance or size of the lesions. Subsequent biopsies revealed an unusual neuromatoid pathology in the dermis, in which axons were absent on light and electron microscopy, with neurilemmoma being considered as a possible diagnosis.
一名45岁的巴基斯坦女性前往卡拉奇的一家诊所就诊，其面部和颈部左侧出现色素减退性皮损已有一年病史。初诊时，皮损表面粗糙且感觉减退；在世界上这个麻风病高度流行的地区，临床检查结果提示为斑状结核样麻风。该患者接受了5年的氨苯砜治疗，但皮损的外观和大小均无变化。随后的活检显示真皮内有异常的神经瘤样病理改变，在光镜和电镜下均未见轴突，神经鞘瘤被认为是一种可能的诊断。
