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[低钾血症性横纹肌溶解症与噻嗪类利尿剂。3例临床病例]

[Hypokalemic rhabdomyolysis and thiazide diuretics. 3 clinical cases].

作者信息

Girola S S, Mazzone A, Moroni M, Porta C, Nastasi G, Notario A

机构信息

Istituto di Terapia Medica, Università degli Studi, IRCCS Policlinico San Matteo di Pavia.

出版信息

Ann Ital Med Int. 1995 Apr-Jun;10(2):134-7.

PMID:7619654
Abstract

Rhabdomyolysis is an acute skeletal muscle disorder characterized by altered integrity of the cell membranes of muscle fiber cells and can be caused by a variety of factors whose nature is not necessarily traumatic. Hypokalemia is one of the most common metabolic causes, accounting for about 14-28% of rhabdomyolytic syndromes. We report and discuss three cases of hypokalemia caused by diuretic treatment with hydrochlorothiazide: the main clinical features were muscle symptoms following massive rhabdomyolysis.

摘要

横纹肌溶解症是一种急性骨骼肌疾病,其特征是肌纤维细胞膜完整性改变,可由多种性质不一定为创伤性的因素引起。低钾血症是最常见的代谢性病因之一,约占横纹肌溶解综合征的14% - 28%。我们报告并讨论三例因氢氯噻嗪利尿治疗导致的低钾血症病例:主要临床特征为大量横纹肌溶解后的肌肉症状。

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