Canelles Gamir P, Herrera Ballester A, Orti Ortín E, Medina Chulia E, Tomé Toyosato A, Benages Martínez A
Unidad de Endoscopia Digestiva, Hospital General Universitario, Valencia.
Gastroenterol Hepatol. 1995 Jan;18(1):1-6.
A group of patients with clinical manifestations suggesting biliary origin in whom diagnostic imaging techniques were negative were studied by duodenal biliary drainage with the aim of identifying whether microcalculi were present in the bilis being responsible for the symptomatology. The problem group was made up of 96 patients with the results being compared with those of a control group (without biliary disease) including 45 subjects. Duodenal biliary drainage was analyzed for the detection of microlithiasis in the biliary sediment in all the subjects. The analysis was positive in 46 (47.9%) of the patients with biliary clinical manifestations while analysis was positive in only 5 (11.2%) of the control group with the differences being statistically significant. Seventeen of the 46 positive patients underwent surgery demonstrating biliary disease in all (chronic cholecystitis). All these patients remained asymptomatic except one on follow up with 94.1% cure by cholecystectomy being achieved. The authors conclude that duodenal biliary drainage is a highly profitable, complication-free and easily performed diagnostic technique for the detection of microlithiasis which should be regularly used in patients with symptoms suggestive of biliary origin and complementary negative explorations.
对一组临床表现提示为胆源性但诊断性影像学检查结果为阴性的患者进行了十二指肠胆汁引流研究,目的是确定胆汁中是否存在导致症状的微结石。问题组由96例患者组成,其结果与包括45名受试者的对照组(无胆道疾病)的结果进行比较。对所有受试者的十二指肠胆汁引流进行分析,以检测胆汁沉淀物中的微结石症。在有胆道临床表现的患者中,46例(47.9%)分析呈阳性,而在对照组中只有5例(11.2%)分析呈阳性,差异具有统计学意义。46例阳性患者中有17例接受了手术,所有患者均显示有胆道疾病(慢性胆囊炎)。除1例患者外,所有这些患者在随访中均无症状,胆囊切除术的治愈率达到94.1%。作者得出结论,十二指肠胆汁引流是一种用于检测微结石症的高效益、无并发症且易于实施的诊断技术,应定期用于有胆源性症状且辅助检查结果为阴性的患者。