Oishi K, Yoshida O, Schroeder F H
Department of Urology, Faculty of Medicine, Kyoto University.
Cancer Surv. 1995;23:267-80.
The age adjusted death rate from prostate cancer in Japan is one of the lowest in the world but is rising steadily. The vast majority of cases of prostate cancer remain undetected during life, the prevalence of prostate cancer detected at autopsy being 2800 times that of lethal cancer in Japanese in Japan, 570 times in whites in the USA and 470 times in blacks in the USA. A case-control study of prostate cancer carried out in Japan and the Netherlands revealed a number of statistically significant risk factors, including rural residence, more brothers, colon neoplasms in relatives, no morning erections, frequent sexual intercourse in 30s, episodes of sexually transmitted disease, lower plasma testosterone and dihydrotestosterone concentrations and lower beta-carotene intake.
日本前列腺癌的年龄调整死亡率是世界上最低的之一，但正在稳步上升。绝大多数前列腺癌病例在生前未被发现，在日本，尸检时检测到的前列腺癌患病率是致命性癌症的2800倍，在美国白人中是570倍，在美国黑人中是470倍。在日本和荷兰进行的一项前列腺癌病例对照研究揭示了一些具有统计学意义的风险因素，包括居住在农村、兄弟较多、亲属中有结肠肿瘤、无晨勃、30多岁时性交频繁、有性传播疾病史、血浆睾酮和双氢睾酮浓度较低以及β-胡萝卜素摄入量较低。
