Thomas J O, Ogunbiyi J O
Department of Pathology, University College Hospital, Ibadan, Nigeria.
East Afr Med J. 1995 Apr;72(4):231-3.
Recent reviews of thyroid malignancies indicate an increasing incidence with suggestions that incidence and regional variation in histological types may be related to socioeconomic and environmental factors. We studied 137 cases of thyroid cancer occurring in the University College Hospital, Ibadan over a 20-year period (1965-1984), consisting of 45 males and 92 females. The ages ranged from 8-85 years with a mean age of 40 years. Papillary carcinoma constituted 45.3% cases, whilst follicular carcinoma made up 44.5% with a frequency ratio of 1:1. Seven cases (5%) of medullary carcinoma were seen and these had a male/female ratio of 1.3:1 with an average age of occurrence of 34 years. In contrast to previous studies from this environment, there is a suggestion of an increasing trend in the incidence of papillary carcinoma in our centre. The significance of changing socio-economic and environmental factors in the region are highlighted.
近期对甲状腺恶性肿瘤的综述表明其发病率呈上升趋势，且组织学类型的发病率及区域差异可能与社会经济和环境因素有关。我们研究了在伊巴丹大学学院医院20年间（1965 - 1984年）发生的137例甲状腺癌病例，其中男性45例，女性92例。年龄范围为8至85岁，平均年龄为40岁。乳头状癌占病例的45.3%，滤泡状癌占44.5%，频率比为1:1。观察到7例（5%）髓样癌，其男女比例为1.3:1，平均发病年龄为34岁。与该地区先前的研究不同，我们中心乳头状癌的发病率有上升趋势。突出了该地区社会经济和环境因素变化的重要性。
