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[炎症状态下外周血中性粒细胞的溶酶体酸性磷酸酶活性]

[The lysosomal acid phosphatase activity of the peripheral blood neutrophilic leukocytes in inflammation].

作者信息

Zelen'ko O A

出版信息

Fiziol Zh (1994). 1994 May-Aug;40(3-4):107-11.

PMID:7621947
Abstract

The investigation was carried out on 56 adult rabbits. The level of activity of lysosomal acid phosphatase in blood, its dependence on a degree of degranulation of granulocytes and interaction of these processes on parametres of some humoral systems of blood controlled by the Hageman factor were investigated under conditions of aseptic inflammation caused by intramuscular injection of formaline. The conclusion is made that exocytosis of lysosomal enzymes and changes in activity levels of some humoral systems controlled by them under conditions of inflammation are nonspecific components of a general adaptation syndrome.

摘要

对56只成年兔子进行了研究。在肌肉注射福尔马林引起的无菌性炎症条件下,研究了血液中溶酶体酸性磷酸酶的活性水平、其对粒细胞脱颗粒程度的依赖性以及这些过程对由Hageman因子控制的血液中某些体液系统参数的相互作用。得出的结论是,在炎症条件下,溶酶体酶的胞吐作用以及由它们控制的某些体液系统活性水平的变化是一般适应综合征的非特异性组成部分。

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