Myshunina T M, Kononenko V Ia, Mikosha O S, Tron'ko M D
Fiziol Zh (1994). 1994 May-Aug;40(3-4):9-15.
Activity of glutamate decarboxylase, a GABA synthesis enzyme, and intensity of its reception in the adrenal cortex and hypothalamus of guinea pigs and rats with normal and stimulated steroidogenesis was investigated. It has been shown that in the adrenal cortex there is a metabolic system which provides GABA synthesis from glutamate and mechanisms of GABA reception by plasmatic membranes. Mediator synthesis in the adrenal cortex is subjected to seasonal changes, GABA synthesis and reception selectively vary with administration of ACTH, prolactin and maintenance of animals on a diet with an excess of potassium ions.
对正常及刺激类固醇生成的豚鼠和大鼠肾上腺皮质及下丘脑内γ-氨基丁酸合成酶谷氨酸脱羧酶的活性及其受体强度进行了研究。结果表明，肾上腺皮质存在一个由谷氨酸合成γ-氨基丁酸的代谢系统以及质膜γ-氨基丁酸受体机制。肾上腺皮质中的介质合成存在季节性变化，γ-氨基丁酸的合成与受体在促肾上腺皮质激素、催乳素给药以及动物食用含过量钾离子的日粮时会选择性地发生变化。
