Brealey C J, Lawrence D K
J Chromatogr. 1979 Jan 21;168(2):461-9. doi: 10.1016/0021-9673(79)80017-5.
Pirimiphos methyl is an organophosphorus insecticide which is rapidly metabolised by plants and animals to several modified triesters and free hydroxyprimidines. A method is described for the determination by reversed-phase high-performance liquid chromatography of pirimiphos methyl and its five major metabolites in plasma and urine. Separations were performed by isocratic and gradient elutions from short columns packed with SAS-Hypersil, a relatively new column packing.
甲基嘧啶磷是一种有机磷杀虫剂，它能被植物和动物迅速代谢为几种改性三酯和游离羟基嘧啶。本文描述了一种用反相高效液相色谱法测定血浆和尿液中甲基嘧啶磷及其五种主要代谢物的方法。分离是通过在装有SAS-Hypersil（一种相对较新的柱填料）的短柱上进行等度洗脱和梯度洗脱来完成的。
